Publications

The publications listed below present the scientific work related to the NDD Profiles project.

Interactive Tools

Three self-contained HTML tools — no installation, no server, no login required.
Download a file, open it in any modern browser, and run it offline.

  • Brain Region Impact Configurator: Select one or more YBA brain regions, set their affected percentage, and instantly see the predicted connectivity impact on all downstream regions — ranked by severity with 95% confidence intervals.
  • Brain Function NDD Impact Simulator: Simulate the effect of neurodegenerative impairment on brain function using a sigmoid network model. Adjust regional impairment levels across all 38 left/right paired regions and observe global function loss in real time.
  • NDD Brain Region Networks — 3D Viewer: Explore the region-level brain network for each of the 29 neurodegenerative diseases in an interactive 3D graph. Select any disease to see affected regions as nodes and their anatomical connections as edges, colour-coded by lobe.